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Double-membrane MDVs originate from the inner membrane of the mitochondria containing proteins from the mitochondrial matrix, and use PDH as a marker (Soubannier et al

(2012), is characterized by iron-dependent accumulation of lipid peroxides, distinguishing it from classical cell death modalities such as apoptosis, necrosis, and autophagy, ferroptosis exhibits a stronger dependence on intracellular iron than other regulated cell death pathways

BergANorbergAMartlingCRGamrinLRooyackersOWernermanJet al

Inoue K, Tsuda M

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

Kultti A, Pasonen-Seppnen S, Jauhiainen M, Rilla KJ, Krn R, Pyri E, et al