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doi: 10.1016/j.febslet.2007.11.011 57 OladimejiPCuiHZhangCChenT

In mammalian cells, -glutamylcysteine synthetase is effectively inhibited by a GSH feedback, whereas glutathione synthetase is not subject to the negative feedback 9,30

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Concluding remarks The transcription factor NRF2 is central to the regulatory network governing cellular defenses against toxic and oxidative insults

*Correspondence: Yuanyuan Lin, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers