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doi: 10.1021/ar200024c 42 ZhangLWangXCuetoREffiCZhangYTanHet al

Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose

Consider adding at least one evidence-based ingredient and aligning marketing language with available data to avoid overstating efficacy

This membrane-permeable probe becomes fluorescent upon hydrolysis in endolysosomes, releasing membrane-impermeable fluorescent cresyl violet, which is trapped in endolysosomes

Immunohistochemical examination Caspase-3 as an apoptotic marker

Carmichael RE, Wilkinson KA, Craig TJ