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Although not strictly identical, similar patterns of CSPs observed in BRD4 ET per residue upon titration with either ASXLs suggested that all ASXLs can associate with BRD4 ET , and each occupies the same binding site of BRD4 ET (Fig

10.3390/ijms15058591 12

10.1016/j.addr.2023.115086 184 MarinelliL.Martin-GallausiauxC.BourhisJ

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Antioxidant Defense: It neutralizes harmful free radicals and oxidative stress, preventing cell damage

3 Effects of metformin on endometriosis Endometriosis is a common gynecological condition affecting 5%15% of women of reproductive age worldwide, leading to pain, infertility, and systemic inflammation (Taylor et al., 2021)