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Additionally, ferroptotic cells release high-mobility group box 1 (HMGB1), which, through the advanced glycosylation end-product receptor (AGER), enhances macrophage recruitment and inflammatory responses (Fig

And unlike tirzepatide or semaglutide, phentermine is not a GLP-1 agonist , so it does not provide the metabolic and glycemic benefits that incretin-based therapies deliver

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