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The primary end point was RFS, defined as the time from randomization until the date of first recurrence or death from any cause

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Receptor selectivity, tissue exposure, formulation, dose, timing, model choice, and safety signals all sit upstream

All these applications demonstrated that RFMS method coupled to HILIC-UPLC-ESI-MS, represents a sensitive high throughput approach for serum N-glycome analysis and a valuable option for glycan detection and separation particularly for isomeric species