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Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons

3.1 Traditional drug therapy Methotrexate is the most commonly used DMARD due to its low cost and decades of clinical experience, and considered as the gold standard drug for RA treatment (88)

Cell cultures COS-7 cells (ATCC, CRL-1651), EA.hy926 cells (ATCC, CRL-2922), A549 cells (ATCC, CRM-CCL-185) were cultured in DMEM/high glucose (Gibco) supplemented with 10% FBS (Gibco), penicillin (100 U/mL), and streptomycin (100 mg/mL) (HyClone)

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This plant belongs to the Alismataceae family