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Inhibitors of NOX1/4, such as GKT137831 (Setanaxib), have progressed to phase II studies for fibrotic and inflammatory conditions, including primary biliary cholangitis and diabetic nephropathy

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J Cereb Blood Flow Metab 34:15001510 Hosp F, Gutirrez-ngel S, Schaefer MH, Cox J, Meissner F, Hipp MS, Hartl FU, Klein R, Dudanova I, Mann M (2017) Spatiotemporal Proteomic Profiling of Huntingtons Disease Inclusions Reveals Widespread Loss of Protein Function

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