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Redox Signal 13 , 11331144 (2010)

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Front Pharmacol 11:615598 Dorsey E et al (2018) The emerging evidence of the Parkinson pandemic

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Week 1: 50mcg nightly Week 2: 100mcg nightly (if Week 1 tolerated well) Weeks 3-4: 150mcg nightly (if no adverse effects) Weeks 5-8: 200-300mcg nightly (target maintenance dose) Gradual titration helps identify your minimum effective dose while avoiding unnecessary exposure to higher amounts