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Melatonin alleviates the heat stress-induced impairment of Sertoli cells by reprogramming glucose metabolism

Neuron 105, 10771093 e7

As a result, NRF2 is freed from Keap1, with which it forms a complex, and is translocated into the nucleus where it binds to antioxidant responsive elements (AREs) in the promoters of target genes (Fig

The table below summarizes some of the available treatment options that have shown potential in experimental models and their clinical status (Table 1)

In brief, the Caco-2 cells were cultured in Dulbeccos modified Eagles medium (DMEM) supplemented with 10% fetal bovine serum (FBS) at 37C with 5% CO 2