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Cytokines released in response to oxidative stress further contribute to systemic inflammation, reinforcing oxidative stress, and thus leading to chronic inflammation (52)

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We have previously studied the transcriptional regulation of cabbage in response to Xcc during the early infection stage by transcriptomic analysis, but the lack of the control plants in the study limits our ability to reveal truly significant expressed genes as well as the molecular pathways in cabbages responses to Xcc infection (Sun et al., 2021)

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10,478 Notably, a clinical trial of adoptive Treg transfer in T1D revealed that lower fold expansion of Tregs was associated with better C-peptide preservation, suggesting that excessive in vitro expansion may not necessarily improve therapeutic efficacy