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These alterations exacerbate systemic inflammation and promote the migration of activated immune cells to the skin, intensifying keratinocyte hyperproliferation and plaque formation

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1 Introduction Chronic pain affects approximately 20% of the adult population in Western countries and represents a major public health challenge due to its multifactorial nature and significant impact on quality of life (1)

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It's best to consult your health care professional for timing and dosage levels that are best for you