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However, the finding of vascular contact must match the clinical picture and the response to therapy to confirm that this is truly the cause and to justify surgical treatment

No significant inhibition of COMT, GNMT, or PNMT observed

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305,306 This impaired vasodilatory response appears before decreases in nerve conduction velocity (NCV) and contributes to reduced endoneurial perfusion and ischemia

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Axitinib emerges as a promising agent with beneficial effects on neurodegeneration within animal models of AD (Singh and Choi 2021)