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Similarly, another novel two-stage fermentation, including culture and fermentation stages, was also developed based on the analysis of conventional pH shock fermentation, achieving -PL yield and productivity increases to 32.22 g/L and 5.86 g/L/day, which were 32.3% and 36.6% higher, respectively, than those of the conventional fermentation [82]

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This work was supported by the Lundbeck Foundation (fellowship R238-2016-2859), the BioInnovation Institute (grant number NNF20OC0063538) and the Novo Nordisk Foundation (grant numbers NNF17OC0026114 and NNF22OC0073778)

Mesnage R, Benbrook C, Antoniou MN

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