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Internat J Nanomed

Blocking these channels can lead to membrane depolarization, increasing neuronal excitability and influencing physiological processes such as vascular smooth muscle contraction and neurotransmitter release (Sibille et al., 2015

Sources and further reading Sikiric P, et al

Teratogenicity assessment in pregnant rats receiving 0.2-4 mg/kg intramuscularly during days 6-15 of pregnancy found no effects on fetuses or organ development