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Hu Y, Tian X, Zhao Y, Wang Z, Lin M, Sun R, et al

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F.EngelmanC

MA myeloablative

Results Cryo-EM of full-length human CBS reveals a filamentous architecture We pursued the cryo-EM structure of full-length CBS initially using two constructs: one where an N-terminal His-tag was removed during purification (CBS FL ) and one with a permanent C-terminal His-tag (CBS FL-CHis ) (Supplementary Fig