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Role of NLRP3 inflammasome in Parkinson's disease and therapeutic considerations

141 The leading saRNA drug, MTL-CEBPA, which was developed by MiNA Therapeutics, targets the CCAAT/enhancer-binding protein alpha (CEBPA)

4.9 Ferroptosis in Huntingtons disease HD is an autosomal dominant neurodegenerative disorder caused by CAG repeat expansions in the HTT gene, which encodes mutant huntingtin (mHTT) proteins containing elongated polyglutamine (polyQ) tracts