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Recently we have designed and synthesized AngIV-based small molecules that influence HGF dimerization and in turn Met receptor activation

Spinal discs have an incredibly poor blood supply, a condition known as being 'avascular.' Without robust blood flow, the essential nutrients, oxygen, and growth factors needed for repair just can't get to the injury site efficiently

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Protocol: 2 months on, 2 months off, with a 2-week ramp-up at 5 units before increasing to 8 units for weeks 3 through 8, 5 days on and 2 days off

Overall, the MD data was consistent with the markedly different dynamics observed in the cryo-EM 3DVA with the ECDs undergoing substantially greater dynamic motions in the Cagri-AMY 3 R complex than observed in the parallel rAmy-AMY 3 R complex (Supplementary Fig

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