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GSPT1-Targeted Molecular Glues GSPT1 is a key regulator of the cell cycle, and its dysregulation is closely associated with hematologic malignancies such as acute myeloid leukemia (AML)

They alkylate to give sulfides: RSH + RBr + B RSR + [HB]Br (B = base) Many electrophiles participate in this reaction

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A heat labile soluble factor from bacteroides thetaiotaomicron VPI-5482 specifically increases the galactosylation pattern of HT29-MTX cells

Anti-p-AKT antibody (4060), anti-AKT antibody (4691S) were brought from Cell Signaling Technology Pathways Incorporated

Xiao L, Estell J, Kiilerich P, Ramayo-Caldas Y, Xia Z, Feng Q, Liang S, Pedersen A, Kjeldsen NJ, Liu C, et al