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Ssu72 regulates alveolar macrophage development and allergic airway inflammation by fine-tuning of GM-CSF receptor signaling

One region is termed as G-site, which is hydrophilic in nature and binds the physiological substrate GSH, and another region is the H-site, which assists in binding of electrophilic substrates by providing a hydrophobic environment ( FIGURE 1 GSTs and Stress Response Glutathione S-transferases are known to express at different stages of plant development

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FASEB J (2015) 29(12):476671

3.1.2 Oxidative stress Sies (1991) first defined OS as the accumulation of ROS and cellular damage caused by the imbalance between pro-oxidant and antioxidant systems. ROS are a group of chemically reactive molecules and ions with high oxidizing activity, including superoxide anions, peroxides, and free radicals, which play important roles in cell signaling and tissue homeostasis (Ferreira et al., 2018)

The modulation in the expression and redundancy of GSTs ascertain its enigmatic roles in plant growth and development