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Before we give you a possible time frame to expect your B12 shot to work, consider your relationship with B12

Three local patterns quietly pull B12 down: 1 The GLP-1 wave

Missed doses create troughs that can trigger rebound hunger and disrupt the metabolic adaptations you have built over weeks of consistent use

Its deficiency can lead to scurvy due to impaired collagen formation affecting bones, blood vessels and skin

Appendices Appendix 1: Literature Search Strategies Literature Search - Vitamin B12 Economic Evidence-Based Analysis Search date: June 3, 2013 Databases searched: OVID MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, EMBASE

The sections are: quick reference card, overview, mechanism of action, dosing protocol and titration schedule, reconstitution guide with vial-specific math, side effects and safety, clinical trial data, storage and handling, comparison to related compounds, stacking protocols (if applicable), supplier section, FAQ, sources with citations, and related protocols