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Several candidate non-glutathione disulfide substrates for the dithiol mechanism have been identified using monothiol glutaredoxin mutants as bait proteins for the trapping of Grx(SSR) species (Fig

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In addition, butylmalonate, an inhibitor of DIC, significantly decreased mGSH, suggesting DIC as the major GSH transporter in mouse cerebral cortical mitochondria (Kamga et al., 2010)

Analytical Verification and Review Identity, purity, and structure-relevant data are reviewed against the project objective so the resulting package supports practical decisions rather than only confirming reaction occurrence

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The brain has several mechanisms to neutralize ROS, of which antioxidant scavenging is one of the final lines of defense [6]