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Reactive oxygen species mediate endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 signaling, as well as protein synthesis, in vascular smooth muscle cells

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The relationship between gut and skin microbiota has become a significant research focus, highlighting a bidirectional communication pathway known as the gut-skin axis, which links the skin microbiota to the enteromembrane system

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CD25 upregulation is associated with the expression of regulatory T cells (Treg), which play a crucial role in immunological tolerance by suppressing immune response generation and activating CD8+ cells and NK cells, thus aiding in immune escape (70, 71)