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Structure of the blood-brain barrier and its role in the transport of amino acids

Psychiatry 40 KimT

Wang M , Bensinger M, Martin T, Alsina M, Siegel DS, Gabrail NY, Hari P, Singhal S, Vescio RA, Assouline SE, Kunkel LA, Vallone M, Wong A, Niesvizk R

The R144C change in the CYP2C9 * 2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase

Finally, in relation to the subject of this review, observation of faster proteolysis rates in certain proteins, compared to structured counterparts, provided an early indicator of intrinsic disorder