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Indeed, inflammatory mediators (including glutamate) produced by reactive neuroglia can trigger intracellular signaling cascades that can alter mitochondrial metabolism including respiratory chain enzyme activity (this may explain increased lactate in the CSF of ME/CFS patients) (Shungu et al., 2012)

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According to NSF International, certified RO and activated carbon filters can effectively reduce various chemical contaminants, providing safer drinking water beyond what boiling alone can achieve (NSF, 2023)

Dec 2010;30(6):281-4

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