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This approach involves introducing autologous or allogeneic adult cells or stem cells from the patient into the degenerated IVD in a targeted manner

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Nonetheless, NMDA-induced ISR is an ATF4-independent dephosphorylation of eukaryotic translation initiation factor 2 (eIF2) [113]

It is unclear whether this would be relevant to the flare itself or perhaps to future flares

[DOI] [PMC free article] [PubMed] [Google Scholar] 259.Shiffman J, Smith S