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In primary astrocyte OGD/R experiments, IC II (6.25 M) enhanced Nrf2 transcriptional activity, promoted its nuclear translocation, and activated the OXPHOS/NF-B/ferroptosis axis

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BPC-157 is particularly powerful for localized injury healing especially tendons, ligaments, and the GI tract

Incubation with GSSG led to further oxidation of both proteins presumably due to glutathionylation or other oxidations of cysteines outside the active site

10.1016/j.phrs.2020.105079 28 LiWGuoY.XuZ.LiF.DongY.XuF

Other studies have shown that changes in certain factors can regulate the expression of HGF and c-Met to regulate the HGF/c-Met axis