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NRF-2 translocated to the nucleus, not by direct regulation of mRNA, and raised the expression of genes that encode antioxidant enzymes [106]

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Moreover, after the activation of K-Ras and Akt in transformed cells, 60% of the total FADH 2 and NADH 2 are synthesized from glutamine, while only 30% is derived from glucose 140

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