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Iodine deficiency can result in nodular goiter, where thyroid antigens are secreted from the abnormal gland, causing anti-thyroid antibodies to be present in the circulation

New England Journal of Medicine (2007) 2

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Acids Res 51:W207W212 Kramer JM, Staveley BE (2003) GAL4 causes developmental defects and apoptosis when expressed in the developing eye of Drosophila melanogaster