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FG-4592, a novel oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), maintains hemoglobin levels and lowers cholesterol in hemodialysis (HD) patients: phase 2 comparison with epoetin alfa [abstract]

These medications excel at glycemic control and produce substantial weight loss through mechanisms centered on insulin secretion enhancement, glucagon suppression, and central appetite regulation via GLP-1 pathways