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However, even when sufficient tumor-specific T-cell clones are present, their functional state and differentiation fate within the immunosuppressive TME are equally critical, as an unsustainable immune response ultimately leads to treatment failure

3b indicated a strong GoH3-induced reduction of growth

MA13.07 TROPION-Lung02: initial results for datopotamab deruxtecan plus pembrolizumab and platinum chemotherapy in advanced NSCLC

Dose interruptions or reductions may be required for side effects (e.g., high hemoglobin, hypertension, bone pain)

Nurliyani, N., Harmayani, E., & Sunarti, S

The benefit is that most quick checks no longer need to be scheduled visits