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For histological and immunofluorescence stainings, the aorta was perfused with saline followed by 1.5% agarose before harvesting

Besides, optic atrophy type 1 protein (OPA1) inhibition prevented mitophagy intermediates overload and mitigated methionine-choline-deficient (MCD) diet-promoted liver damage [106]

Tgf-B in hepatic stellate cell activation and liver fibrogenesisUpdated 2019

Yao Q, Cui J, Zhu Y, et al

CNS target engagement will be assessed by measuring levels of key senescence markers in CSF at baseline and after three months treatment with senolytics