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But it should be noted that at meantime of brain protection, BBB also excludes more than 98% of small-molecule drugs and all macromolecular therapeutics from access to the brain

Efficacy of pharmacological and microbiota-based therapies in preclinical models of autism spectrum disorder: a systematic review

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Nevertheless, anti-dengue agents or DENV inhibitors which are protective towards two or three serotypes should be promoted to further testing stage

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Similarly, supplementation with daidzein was shown to reduce the level of myeloperoxidase MPO and inhibit the expression of TNF-, IL-1, and IL-6, in the colonic tissues, inhibiting the production of NO and prostaglandin E2 in LPS-stimulated RAW 264.7 macrophages [189]