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After binding of the IFN- proinflammatory cytokine to its receptor, the Janus kinase (JAK)/signal transducers and activators of transcription (STAT) pathway is activated and stimulates the transcription of the chemokine ligands CXCL9 and CXCL10 [53]

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L., Afjehi-Sadat, L., Heiss, E

A higher proportion of patients receiving elafibranor met either endpoint compared with placebo, regardless of baseline ALP levels, and lower baseline ALP levels yielded higher response rates