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Jump to: Who should never take weight-loss injections | Conditions that need extra caution | Medications that interact | Pregnancy, breastfeeding and age | If you are scheduled for surgery | When to stop and seek help | Questions to ask your GP | Frequently asked questions | Take home message You shouldnt take weight-loss injections like Wegovy (semaglutide) or Mounjaro (tirzepatide) if you have a personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2 (MEN-2), type 1 diabetes, or have had a serious allergic reaction to a GLP-1 medication

When a man begins TRT, his body senses the influx of testosterone and reduces or stops natural LH production

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If you are severely obese and need to lose 25-30%+ of your body weight to reach a healthy range, semaglutide 14-15% average may not be enough

If you have pernicious anemia, malabsorption, or prior gastric surgery, your gut cant absorb pills well enough