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PubMed 67

CHRIS MASTERJOHN: Yeah, I would put grapeseed oil in the category of a seed oil that I wouldnt consume in high quantities

Chikweto A, McNeil P, Bhaiyat MI, Stone D, and Sharma RN

In the case of these mutual interactions, a major factor that should be noticed is the accessibility of vitamin A, which is dependent on the equilibrium between the enzymes which are responsible for the production or inactivation of the RA RAR or could be limiting in rigorous nutritional deficiencies (180)

These include: Nausea (most common, especially during dose escalation) Vomiting Diarrhea Constipation Reduced appetite (expected and part of the mechanism) Abdominal discomfort These effects are most pronounced during dose titration and tend to diminish over time as the body adapts