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This combination can also trigger changes in oncogenes like RAS mutations, which encode p21, suppress tumor suppressor genes, and cause DNA damage, ultimately leading to esophageal squamous cell carcinoma (ESCC) [172]

Although Hmox1 is usually regarded as a protective protein, Menon et al

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The next era of radiation biology should thus prioritize holistic, predictive, and regenerative solutions with direct clinical impact

A spectrophotometer (Shimadzu UV-1700, Tokyo, Japan) was used to measure the optical density of the solution at 662 and 645 nm (for Ch a and b , respectively) and 470 nm (for TCAR)

Furthermore, E2 deficiency impairs fatty acid oxidation by downregulating carnitine palmitoyltransferase I, a key enzyme responsible for mitochondrial fatty acid uptake and -oxidation