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Similarly, disrupted proline and alanine metabolism contribute to tumor growth, aggressiveness, and inflammation, suggesting a key role for these pathways in malignant glioma progression [142,143,144]

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Cell subpopulations with high OXPHOS activity consistently exhibit greater drug resistance, suggesting that mitochondrial metabolic heterogeneity may serve as a critical biomarker for resistance stratification and therapeutic classification [66]

Funding This work has been supported by a recurring unrestricted gift from the Dr

In contrast, Hong Guo 1 exhibited the lowest resveratrol content (0.95 mg/g), which was not significantly different from Su Bai Shen, Lv Shen Zi 2, Gui Hua Mi, Tian Sang 202, Da Ma Ya, and Ju Shen