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To address tuftsins rapid enzymatic degradation, researchers extended the original tetrapeptide sequence at the C-terminus with the tripeptide Pro-Gly-Pro, yielding the final heptapeptide structure Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)

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This detoxification mechanism keeps sensitive organs safe from accumulating damaging toxins

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This study clarifies a critical variable in gerotherapeutics: the route and duration of administration do not simply alter the magnitude of a drugs efficacy