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We also observed that the binding of the E protein with TMED10 does not inhibit but rather enhances the association between TMED10 and IL1 (Supplementary Fig

Assembly of the MAC is terminated by vitronectin, clusterin, and FHR-1, respectively

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5.2.3 Bottlenecks and opportunities in clinical translation While ferroptosis-targeted strategies show promise in OA models, the translation to clinical settings remains hindered by key limitations in safety, efficacy, and delivery