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The amount of glutathione in the glutathione Sepharose 4B beads was estimated according to the assumption (according to the manufacturere's information) that there are about 200400 mol glutathione/g dried beads

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Activated microglia and astrocytes release pro-inflammatory cytokines, including interleukin-1 (IL-1), interleukin-1 (IL-1), and tumor necrosis factor (TNF-), which exacerbate neuronal injury and disease progression (3, 4)