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Unlike cigarette testing machines, which were calibrated to smoke the putative reduced-risk cigarettes in a standardised way, smokers compensated for the lower delivery of nicotine by taking more and deeper puffs per cigarette, smoking more and occluding the tiny ventilation holes on the filters with their fingers

lethal concn in human blood: 550.0 ug/ml (55.0 mg %) [Winek, C.L

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When these receptors are empty, your brain is telling you to fill them again, which is how addiction occurs. When nicotine receptors are filled, dopaminethe body's feel-good chemicalis released, which is why people become addicted to nicotine so quicklythey begin to crave the feeling of dopamine release

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Meanwhile, a 2013 survey of New Zealanders found that 46% percent of smokers supported banning cigarettes within 10 years