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In glioma, few studies have focused on correlations between transcriptional cell state and metabolism (Bonnay et al, 2020

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Numerous candidate targets have been proposed ( Table 2 ), which provide a basis for the precise application of CAR T-cell therapy.The hinge region connects the scFv to the transmembrane domain, providing structural flexibility and facilitating optimal spatial orientation between the CAR and its cognate antigen

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