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Ascorbate inhibits platelet-endothelial adhesion in an in-vitro model of sepsis via reduced endothelial surface P-selectin expression

Its important to know which one came first

However, the extraction method is expensive and not very reasonable in reality

At physiological levels, ROS function as signaling molecules in various signaling pathways, while high levels are toxic to mitochondria and cells (22)

Under physiological conditions, the immediate product of the reaction, the monodehydroascorbate radical, is reduced back to ascorbate by a monodehydroascorbate reductase (monodehydroascorbate reductase (NADH)) enzyme

Particularly, it had excellent anti-tumor properties without inducing observable systemic toxicity owing to efficient DOX and SOR loading and release as well as the HCC specific targeting peptide SP94