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Future prospective, multi-center cohort studies are needed to confirm these findings and improve our understanding of how EGFR mutation contributes to prognosis and clinical outcomes

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Steroids may increase or decrease motility and number of spermatozoa in some patients

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E-cigarettes are developed to maximize nicotine delivery (e.g., via nicotine salts, which make high concentrations of nicotine more palatable76), and some e-cigarette brands are now owned by tobacco companies.77 , 78 E-cigarette use with nicotine may reduce harms from smoking but does not address nicotine addiction, given that nicotine may continue to be consumed long term