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Regulatory agencies can recommend that the drug sponsor perform complementary studies to assess the ability of consumers to correctly self-select the drug for their condition

Through these mechanisms, even relatively low levels of active compounds can generate a fine-tuned yet coordinated regulation of critical signaling pathways such as Nrf2, NF-B, and apoptosis ultimately producing a pronounced and clinically meaningful physiological effect [52]

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Similar trends were also found among other populations, although no statistically significant difference was found in some genetic models

10.1016/j.fsi.2023.109135 38 MarshallS

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