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645 However, the primary endpoint of improved SNCV was not met, and further studies remain uncertain

Restoring Gln levels through dietary or pharmacological means may offer a promising adjunctive strategy to GFD, helping to reduce mucosal damage and support gut healing

137 In addition, adipose MSCs, hair follicle MSCs, and dental pulp MSCs reduce inflammatory responses, promote mucosal healing, and improve intestinal barrier function

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Additional confirmational assays, such as Western blotting, are required to confirm the expression level of proteins such as BCL-2, TLR4, and other inflammatory mediators

It has been suggested that successful treatments need to neutralize the activity of recirculating memory CD8 + T cells or memory cells residing in melanocytes (e.g., by immunosuppression) to prevent disease progression (Riding and Harris, 2019)