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-ketoglutarate ( -KG ) derived from the glutaminase-based catabolism of glutamine provides fuel for the tricarboxylic acid cycle (TCA) in pancreatic cancer cells

Human neuropeptide Y (hNPY), a highly potent 36-amino-acid neurotransmitter and bioactive peptide, exhibits extensive distribution throughout the central nervous system (CNS), peripheral nervous system (PNS), and their associated tissues, organs, and glands 9

The ensuing dysregulation triggers oxidative stress, mitochondrial dysfunction, neuroinflammation, as well as activation of apoptotic pathways, ultimately culminating in neurodegeneration 60

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Ein niedriger Glutathionspiegel begnstigt ein stark geschwchtes Immunsystem, was den Krper fr Krankheiten zu einem leichten Ziel werden lsst