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Therapeutic inhibition of the potential proinflammatory and profibrogenic activity of Th17 cells may be especially pertinent in advanced stages of MASH

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However, white matter OL lineage cells are more intrinsically regulated vs those in the gray matter, as transplantations into the adult mouse cerebral cortex revealed that white matter-derived cells differentiated into mature OLs in both niches with equal efficiency, whereas gray matter-derived cells did not 75

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Khazai N, Judd SE, Tangpricha V