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Cytotoxicity of ungeremine towards multi-factorial drug resistant cancer cells and induction of apoptosis, ferroptosis, necroptosis and autophagy

These findings, along with the fact that the lung can normally maintain GSH for long periods even with the oxidant burden of CS, lend credence to the theory that disease symptoms could arise when adaptive responses fail or are dysfunctional

As an important transcription factor, Nrf2 can not only regulate SLC7A11 transcription, but also up-regulate the expression of GSS and GCLC, which are key rate-limiting enzymes for GSH synthesis (Sun et al., 2016a

Because phenylephrine is a potent -1-agonist, it dramatically increases peripheral vascular resistance and afterload (Medical Advisory Board 2026a)

Glutathione as a Depigmenting Agent: An Overview

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